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KMID : 0371319840260060699
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Journal of the Korean Surgical Society
1984 Volume.26 No. 6 p.699 ~ p.704
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A Comparative Study of Pulling Strength and Histopathologic Findings in Microvascular Anastomosis by use of Black Silk, Polyglycolic Acid, and Nylon
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Abstract
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To determine the pulling strength and histopatholgy of various suture materials, microvascular anastomosis is performed on the mouse femoral artery by use of 10-0 black silk, nylon and polyglycolic acid. 10 days after anastomoses, geometric means of pulling strength are; control group; 126.0±29.4 gm, black silk group; 83.4±20.6 gm, nylon group; 92.4±19.4gm, and polyglycolic acid group; 74.2±21.0 gm.
There is a significant difference betweer the control group and anastomosed groups(p<0. 01). Between polyglycolic acid group and nylon group, there is also a significant difference (p<0.05).
On histopathologic examination, medial.necrosis and perivascular inflammatory cell infiltration are observed in all groups. Tissue reaction around the suture materials is most severe in polyglycolic acid group and minimum in nylon group. Considering above result 10 days after anastomosis, non absorbable suture materials, especially nylon, is more favorable in microvascular anastomosis.
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